Work

Sinonasal Ewing sarcoma misdiagnosed as recurrent glomangiopericytoma: Case report and literature review

Year: 2021

Type: article

Abstract: We present the case of a patient with a sinonasal mass diagnosed as glomangiopericytoma on initial resection. The patient experienced multiple recurrences over ten years, undergoing endoscopic resection each time and ultimately adjunctive radiation therapy. Cytogenetic testing of the fourth recurrence was positive for FUS-ERG fusion, a genetic abnormality seen in a rare subset of Ewing tumors and the first case to be described in a sinonasal tumor. Given the emergence of new immunophenotyping, clinicians should exercise a low threshold for cytogenetic testing in cases where a tumor exhibits characteristics atypical of the initial pathological diagnosis.

Source: Otolaryngology Case Reports

DOI: 10.1016/j.xocr.2021.100369

Authors: Alice E. Huang, Peter H. Hwang, Jonathan H. Lin, Michael Chang

Institutions: Stanford Health Care, Stanford Medicine, Stanford University

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $750