Work

Induction of SREBP1 degradation coupled with suppression of SREBP1-mediated lipogenesis impacts the response of EGFR mutant NSCLC cells to osimertinib

Year: 2021

Type: article

Source: Oncogene

DOI: 10.1038/s41388-021-02057-0

Authors: Zhen Chen, Danlei Yu, Taofeek K. Owonikoko, Suresh S. Ramalingam, Shi-Yong Sun

Institutions: Emory University, Winship Cancer Institute, University of Pittsburgh, UPMC Hillman Cancer Center

Language: English

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute

Awards: G1244491795, c-Myc modulation and its implications in EGFR-targeted cancer therapy, G2320726860, G2917785245, G3707983607, G4696541794, ECOG-ACRIN Thoracic Malignancies Integrated Translational Science Center, G5867855652, G6846935373, Modulation of death receptor 4 in EGFR-targeted cancer therapy, G7682862975, G7755794518, G8149540028

OpenAlex ID: W3206710376

FWCI: 3.109

Cites: 30

Cited by: 35

Related to: 10