Work

Associations between vitamin D levels and glucose metabolism markers among pregnant women and their infants in Puerto Rico

Year: 2021

Type: article

Study design: Observational Study

Abstract: INTRODUCTION: Objectives: low vitamin D during pregnancy is common and could adversely affect health outcomes. This study evaluated vitamin D status during pregnancy and early in life, and its association with glucose metabolism. Methods: maternal serum 25(OH)D, glucose, and insulin levels were measured longitudinally during pregnancy in Hispanic women with overweight/obesity (n = 31) and their infants at birth and 4 months. Results: insulin and HOMA-IR levels were higher among women with vitamin D below adequate levels compared to those with adequate levels in pregnancy (p < 0.05). Late in pregnancy, as vitamin D increased by one unit (ng/mL), insulin decreased by 0.44 units and HOMA-IR by 0.09 units. Maternal vitamin D late in pregnancy was correlated with infant vitamin D levels at birth (r = 0.89; p < 0.01) and 4 months (r = 0.9; p = 0.04), and with glucose (r = 0.79; p = 0.03) and insulin (r = 0.83; p = 0.04) at 4 months. Conclusion: maternal vitamin D status was associated with maternal and infant glucose metabolism in this sample.

Source: Nutrición Hospitalaria

DOI: 10.20960/nh.03600

Authors: Cristina Palacios, Maria Angelica Trak-Fellermeier, Marytere Melendez, Maribel Campos, Jeremy Pomeroy, Kai Guo, Paul W Franks, Kaumudi Joshipura

Institutions: Florida International University, University of Puerto Rico, Medical Sciences Campus, University of Puerto Rico System, Marshfield Clinic Research Foundation, Marshfield Clinic Research Institute, Lund University, Skåne University Hospital

Language: English

Topic: Vitamin D Research Studies

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: gold

Estimated APC paid: $485

Funders: National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute on Minority Health and Health Disparities, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: RCU for Lifestyle Interventions in Overweight and Obese Pregnant Women Consortium, Preventing excessive gestational weight gain in obese women, Pregnancy and EARly Lifestyle improvement Study (PEARLS), Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT), Weight Management in Obese Pregnant Underserved African American Women, Hispanic Alliance for Clinical and Translational Research (Alliance), Puerto Rico Clinical and Translational Research Consortium (PRCTRC), Expecting Success: Personalized management of body weight during pregnancy, Lifestyle Interventions in Overweight and Obese Pregnant Women

OpenAlex ID: W3206902685

FWCI: 0.333

Cites: 38

Cited by: 3

Related to: 10