Work

Characterization and Inhibition of 1-Deoxy- d -Xylulose 5-Phosphate Reductoisomerase: A Promising Drug Target in Acinetobacter baumannii and Klebsiella pneumoniae

Year: 2021

Type: article

Abstract: in complex with inhibitor FR900098, and cofactors NADPH and magnesium.

Source: ACS Infectious Diseases

DOI: 10.1021/acsinfecdis.1c00132

Authors: Haley S. Ball, Misgina B. Girma, Mosufa Zainab, Iswarduth Soojhawon, Robin D. Couch, Schroeder M. Noble

Institutions: George Mason University, Walter Reed Army Institute of Research

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,000

Funders: U.S. Department of Energy, U.S. Army, National Institute of Allergy and Infectious Diseases

Awards: G1580077915, Inhibition of MEP pathway Isoprenoid Biosynthesis, G426717048, G7639274029

OpenAlex ID: W3207718759

FWCI: 0.951

Cites: 76

Cited by: 18

Related to: 10