Work

MOSTWAS models, TWAS summary statistics, and simulation results for Bhattacharya and Love, 2020

Year: 2020

Type: dataset

Abstract: This compressed folder contains three sub-folders that all pertain to models and results generated with Multi-Omic Strategies for Transcriptome-Wide Association Studies (MOSTWAS): MOSTWAS_Models contains compressed folders for MOSTWAS models trains on TCGA breast cancer and ROS/MAP pre-frontal cortex multi-omic data. Simulations contains Simulation_Results_MOSTWAS.xlsx that provides full simulation results outlined in Bhattacharya and Love, 2020 (paper accompanying MOSTWAS). TWAS_associations contains four Excel files that provide MOSTWAS and local-only TWAS associations for breast cancer-specific survival (using iCOGs GWAS summary statistics), late-onset Alzheimer's disease risk (using IGAP GWAS summary statistics), and major depressive disorder risk (using PGC GWAS and UK Biobank GWAX summary statistics).

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.3755918

Authors: Bhattacharya, Arjun, Love, Michael I.

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4393669353

Cites:

Cited by: 1

Related to: 10