Work

Structural Bioinformatic and Genomic Analyses of RORg Interacting with Cognate Response Elements

Year: 2021

Type: article

Abstract: This is a series of scripts or script outputs to accompany a scientific publication examining the DNA-recognition of the nuclear receptor called RORγ. Contained within are scripts used to evaluate genomic distributions of specific DNA-sequences and their functional importance. This deposition also contains scripts used to generate integrative structural models of RORγ on cognate response elements.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.4737543

Authors: Strutzenberg, Timothy S, Griffin, Patrick R

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: Determining the structural basis for ligand-mediated RORγ activation, Optimization of RORgamma-specific agonists as immune activators for a new immunotherapy approach for cancer

OpenAlex ID: W3209592841

FWCI:

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