Acute kidney injury in patients hospitalized with COVID-19 in a Tertiary Care Hospital of Islamabad
Year: 2021
Type: article
Study design: Observational Study
Abstract: Objective: This study is conducted to find out prevalence, risk factor and outcome of acute kidney injury (AKI) in patients admitted with COVID-19 in Pakistani population. Study Design: Retrospective, Observational Study Place and Duration of Study: This study was conducted at the PAF hospital Islamabad from April, 2020 to December, 2020. Materials and Methods: It involved a review of data from electronic hospital records of patients who were aged18 years or older with laboratory-confirmed COVID-19. We describe the frequency of AKI and, AKI recovery, dialysis requirement and adjusted odds ratios (aORs) with mortality. Results: Total 191 COVID-19 patients were enrolled, AKI occurred in total 38 (19.8%) patients and out of them 8(4.2%) patients had severe AKI and required dialysis. Regarding AKI staging, stage 1 was present among 18 (9.4%) patients, 06 (3.1%) had stage 2 and 14 (7.3%) had stage 3 AKI. The patients in ICU developed AKI more frequently stage 1 15.4%, stage 2, 7.7%, and stage 3 by 13.5% respectively. Patients with AKI were more likely to have admission in ICU, requirement for mechanical ventilation and requirement for inotropic support. Mortality was very high among patient with AKI 60.5% as compared to patient with no AKI 13.7%. Conclusion: We found in our study that AKI is a relatively common complication observed among patients hospitalized with COVID-19. It is linked to poor outcome and high mortality.
Source: Medical Forum Monthly
Authors: Muhammad Sajid R. Abbasi, Md Rana Masud, Keith Sultan, Usama Rehman, Sana Nasim, rukhsana Manzoor
Language: English
Topic: Acute Kidney Injury Research
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3209713762