Work

Identification of De Novo Pyrimidine Synthesis as a Targetable Vulnerability in a Novel IDH1 Mutant Engineered Astrocytoma Model

Year: 2021

Type: article

Source: International Journal of Radiation Oncology*Biology*Physics

DOI: 10.1016/j.ijrobp.2021.07.205

Authors: D.D. Shi, A.C. Wang, W. Gao, J. Khanal, M.M. Levitt, R.B. Jennings, S. Signoretti, Q.D. Nguyen, J.E. Endress, M. Xu, S. Gradl, A. Sutter, M. Jeffers, A. Janzer, D.P. Cahill, K.G. Abdullah, K.L. Ligon, I.S. Harris, W.G. Kaelin, S.K. McBrayer

Institutions: Harvard University, Dana-Farber Cancer Institute, Children's Medical Center, The University of Texas Southwestern Medical Center, Brigham and Women's Hospital, Bayer (Germany), Bayer (United States), Massachusetts General Hospital, Boston Children's Hospital, Dana-Farber Brigham Cancer Center, University of Rochester Medicine, University of Rochester, Howard Hughes Medical Institute

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W3211198663

FWCI: 0.22

Cites:

Cited by: 2

Related to: 10