Cross-Linking Mass Spectrometry for Investigating Protein Conformations and Protein–Protein Interactions─A Method for All Seasons
Year: 2021
Type: review
Abstract: . Computational modeling plays a crucial role in deriving 3D-structural information from XL-MS data. Integrating XL-MS with other techniques of structural biology, such as cryo-electron microscopy, has been successful in addressing biological questions that to date could not be answered. XL-MS is therefore expected to play an increasingly important role in structural biology in the future.
Source: Chemical Reviews
Institution: Martin Luther University Halle-Wittenberg
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $5,000
Awards: Zentrum für Innovationskompetenz HALOmem, Nachwuchsgruppe: Kryo-Elektronenmikroskopie von membrangebundenen Protein-Nanomaschinen, G2978818265, G3700064202, SFB 1423: Strukturelle Dynamik der GPCRAktivierung und Signaltransduktion, G542737748, G7072289004, CORONA - CORONAmem - Molekulare Determinaten der differentiellen Wirtsanfälligkeit gegenüber SARS-CoV-2 am Eintrittspunkt, GRK 2467: Intrinsisch ungeordnete Proteine – Molekulare Prinzipien, zelluläre Funktionen und Krankheiten, G821008794, G8213085267
OpenAlex ID: W3212436453