Work

Surface presentation of the noncanonical Wnt5a motif to cytotoxic CD8 + T-cells promotes their mechanotransduction and activation

Year: 2021

Type: article

Abstract: T cells by triggering the noncanonical Wnt signaling. This new mechanoregulatory ligand platform can be widely applied in the fundamental research of mechano-immunology and further the development of novel immunotherapies.

Source: Chemical Communications

DOI: 10.1039/d1cc05194f

Authors: Rui Li, Walida Ali, Chao Ma, Apratim Bajpai, Ngoc Luu, Aarushi Varshney, Camden Riley Rowe, Weiqiang Chen

Institutions: New York University, NYU Langone Health, NYU Langone’s Laura and Isaac Perlmutter Cancer Center

Language: English

Topic: Immunotherapy and Immune Responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Dissecting and engineering CAR T-cell function for optimized Immunotherapy

OpenAlex ID: W3213601065

FWCI: 0.279

Cites: 17

Cited by: 5

Related to: 10