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Neuronal accumulation of peroxidated lipids promotes demyelination and neurodegeneration through the activation of the microglial NLRP3 inflammasome

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Year: 2021
Type: article
Source: Nature Aging
DOI: 10.1038/s43587-021-00130-7
Authors: Guohao Wang, Weiqin Yin, Hyunhee Shin, Qingjun Tian, Wei Lu, Steven X. Hou
Institutions: National Institutes of Health, National Institute of Neurological Disorders and Stroke, Frederick National Laboratory for Cancer Research, National Cancer Institute, Center for Cancer Research, National Institute of Diabetes and Digestive and Kidney Diseases, Fudan University, State Key Laboratory of Genetic Engineering
Language: English

Topic: Neuroinflammation and Neurodegeneration Mechanisms
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Foundation for the National Institutes of Health, U.S. Department of Health and Human Services, National Natural Science Foundation of China, National Institutes of Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke
Awards: G4984284246, G5425204308, Molecular Genetic Study of Stem Cells, Cancer Stem Cells, and Stem Cell Aging, G7475365620, The regulation of synaptic transmission and neural circuit function
OpenAlex ID: W3214055023
FWCI: 1.397
Cites: 51
Cited by: 34
Related to: 10
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