2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations
Year: 2021
Type: article
Abstract: Advanced age, diabetes, and chronic kidney disease not only increase the risk for ischaemic events in chronic coronary syndromes (CCS) but also confer a high bleeding risk during antiplatelet therapy. These special populations may warrant modification of therapy, especially among Asians, who have displayed characteristics that are clinically distinct from Western patients. Previous guidance has been provided regarding the classification of high-risk CCS and the use of newer-generation P2Y12 inhibitors (i.e. ticagrelor and prasugrel) after acute coronary syndromes (ACS) in Asia. The authors summarise evidence on the use of these P2Y12 inhibitors during the transition from ACS to CCS and among special populations. Specifically, they present recommendations on the roles of standard dual antiplatelet therapy, shortened dual antiplatelet therapy and single antiplatelet therapy among patients with coronary artery disease, who are either transitioning from ACS to CCS; elderly; or with chronic kidney disease, diabetes, multivessel coronary artery disease and bleeding events during therapy.
Source: European Cardiology Review
DOI: 10.15420/ecr.2021.35
Authors: Jack Wei Chieh Tan, Derek P Chew, Kin Lam Tsui, Doreen Tan, Dmitry Duplyakov, Ayman Hammoudeh, Bo Zhang, Yi Li, Kai Xu, Paul J Ong, Doni Firman, Habib Gamra, Wael Almahmeed, Jamshed Dalal, Li-Wah Tam, Gabriel Steg, Quang N Nguyen, Junya Ako, Jassim Al Suwaidi, Mark Chan, Mohamed Sobhy, Abdulla Shehab, Wacin Buddhari, Zulu Wang, Alan Yean Yip Fong, Bilgehan Karadag, Byeong-Keuk Kim, Usman Baber, Chee Tang Chin, Ya Ling Han
Institutions: General Hospital of Shenyang Military Region, National Heart Centre Singapore, Sengkang General Hospital, Flinders University, Pamela Youde Nethersole Eastern Hospital, National University of Singapore, Dalian Medical University, First Affiliated Hospital of Dalian Medical University, Tan Tock Seng Hospital, Mount Elizabeth Novena Hospital, University of Indonesia, University of Monastir, Hospital Fatuma Bourguiba Monastir, Cleveland Clinic Abu Dhabi, Kokilaben Dhirubhai Ambani Hospital, Kwong Wah Hospital, Hôpital Bichat-Claude-Bernard, Hanoi Medical University, Kitasato University Hospital, Kitasato University, Hamad Medical Corporation, National University Heart Centre Singapore, Alexandria University, United Arab Emirates University, King Chulalongkorn Memorial Hospital, Istanbul University-Cerrahpaşa, Istanbul University, Yonsei University, Severance Hospital, Yonsei University Health System, University of Oklahoma Health Sciences Center
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,146
OpenAlex ID: W3214239493