Work

Author response: Microtubules regulate pancreatic β-cell heterogeneity via spatiotemporal control of insulin secretion hot spots

Year: 2021

Type: peer-review

Abstract: Analysis of insulin secretion patterns in pancreatic islets shows that microtubules control β-cell heterogeneity by regulating initiation and timing of secretion hot spot activity in parallel with Ca2+ signaling.

DOI: 10.7554/elife.59912.sa2

Authors: Kathryn P Trogden, Justin Lee, Kai M Bracey, Kung-Hsien Ho, Hudson McKinney, Xiaodong Zhu, Goker Arpag, Thomas G Folland, Anna B Osipovich, Mark A Magnuson, Marija Zanic, Guoqiang Gu, William R Holmes, Irina Kaverina

Institution: Vanderbilt University

Language: English

Topic: Pancreatic function and diabetes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W3216772006

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