Work

Guiding individual tract activations in the subcallosal cingulate region using image-based biophysical modeling

Year: 2021

Type: article

Abstract: contrast, p40 amplitude was a poor predictor of cingulum bundle perturbation (p¼.18).Contrary to our hypothesis, results showed a similar pattern for the p100 feature, which was associated with forceps minor (r 2 ¼.77, p<.01) rather than cingulum bundle (p¼.07).Exploratory analyses reveal an earlier midline feature that appears more specific to the cingulum bundle.We conclude that EP features may provide an index of stimulation effects on key fiber bundles associated with treatment efficacy to guide optimal DBS parameter selection for individual patients.

Source: Brain stimulation

DOI: 10.1016/j.brs.2021.10.522