Work

Integrated genome and tissue engineering enables screening of cancer vulnerabilities in physiologically relevant perfusable ex vivo cultures

Year: 2021

Type: article

Source: Biomaterials

DOI: 10.1016/j.biomaterials.2021.121276

Authors: Michael Hu, Xin Yi Lei, Jon D. Larson, Melissa McAlonis, Kyle Ford, Daniella McDonald, Krystal Mach, Jessica M. Rusert, Robert J. Wechsler-Reya, Prashant Mali

Institutions: University of California San Diego, Sanford Burnham Prebys Medical Discovery Institute, National Cancer Institute, Ludwig Cancer Research

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, University of California, San Diego, National Human Genome Research Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke

Awards: Systematic mapping of genetic vulnerabilities in head and neck cancer, Research Center for Cancer Systems Biology: Cancer Cell Map Initiative, University of California San Diego Neuroscience Microscopy Imaging Core, Dissecting the interplay of gene regulatory networks and cellular niche on cell fate determination, Next-generation Functional Genetic Screening of Un-screenable Traits, Cancer Center Support Grant (CCSG), Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 Medulloblastoma

OpenAlex ID: W3216907422

FWCI: 0.373

Cites: 87

Cited by: 8

Related to: 10