Analysis plan for primary cohort GWAS for blood lipid levels for the Global Lipids Genetics Consortium
Year: 2021
Type: preprint
Abstract: This protocol describes the guidelines for generating GWAS summary statistics that were provided to all participating cohorts in the Global Lipids Genetics Consortium HRC + 1KGP3 imputation meta-analysis collected jointly with the GIANT consortium. It is applicable for generating the input phenotype and genotype files for use with the rvtests software. Key stages include imputation, generating phenotype files, and running the analysis to generate summary statistics. The exact time needed to carry out this protocol varies depending on the existing genotype files and size of the cohort. The latest version of rvtests is available at: http://zhanxw.github.io/rvtests/
Source: Research Square
Author: Cristen Willer
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W3216970330