Year: 1978
Type: article
Abstract: Complete solubilization of bovine heart-valve gollagen was obtained by using sequential pepsin digestion and extraction with dithiothreitol under non-denaturing conditions. Use of the reducing agent was the crucial step resulting in solubilization. These findings suggest that disulphide-bonded proteins may be in part responsible for the insolubility of bovine heart-valve collagen.
Source: Biochemical Journal
DOI: 10.1042/bj1730337
Authors: S A Jimenez, R I Bashey
Institution: University of Pennsylvania
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: bronze
Funder: University of Pennsylvania
OpenAlex ID: W335197245