Work

Smoking and drug interactions

Year: 2013

Type: article

Abstract: This enzyme induction is rapidly reversed when patients abruptly stop smoking, with a new steady state of CYP1A2 activity reached after approximately one week.20 This reduction in enzyme activity reduces clearance and increases the risk of adverse drug reactions for patients taking drugs metabolised by CYP1A2.20,21 These patients should be regularly asked about their smoking and the extent of their cigarette consumption.16 Clozapine and olanzapineCigarette smoking induces the metabolism of

Source: Australian Prescriber

DOI: 10.18773/austprescr.2013.037

Authors: Catherine Lucas, Jennifer Martin

Institutions: The University of Queensland, Royal Brisbane and Women's Hospital, Princess Alexandra Hospital

Language: English

Topic: Pharmacogenetics and Drug Metabolism

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: University of Queensland