Work

Targeting prostate cancer stem cells for cancer therapy.

Year: 2012

Type: review

Abstract: Prostate cancer is the most common malignant neoplasm in men and the second most frequent cause of cancer death for males in the United States. Recently, emerging evidence suggests that prostate cancer stem cells (CSCs) may play a critical role in the development and progression of prostate cancer. Therefore, targeting prostate CSCs for the prevention of tumor progression and treatment of prostate cancer could become a novel strategy for better treatment of patients diagnosed with prostate cancer. In this review article, we will summarize the most recent advances in the prostate CSCs field, with particular emphasis on targeting prostate CSCs to treat prostate cancer.

Source: PubMed

Authors: Guocan Wang, Zhiwei Wang, Fazlul H Sarkar, Wenyi Wei

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Interplay between Cdh1 and major regulatory pathways in human cancer