BCL2 Expression and BCL2/MYC Dual Expression Predicts Inferior Survival in Primary Central Nervous System Lymphoma
Year: 2014
Type: article
Abstract: Background Primary CNS lymphoma (PCNSL) is a rare type of diffuse large B-cell lymphoma (DLBCL) arising from and usually confined to CNS. Understating of the pathogenesis and prognostic markers is a challenge due to rarity of this neoplasm and paucity of the material available to study. Recent studies have shown that dual expression of MYC and BCL2 in DLBCL contributes to inferior overall survival. The prognostic value of MYC and BCL2 in PCNSL is not well studied.
Source: The Medicine Forum
Authors: Guldeep Uppal, Zixuan Wang, Renu Bajaj, Mark T. Curtis, Charalambos Solomides, Jon Glass, Peter M. Banks, Stephen C. Peiper, Jerald Z. Gong
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W404572197