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Therapy‐related myeloid neoplasms resembling juvenile myelomonocytic leukemia: a case series and review of the literature

Year: 2021
Type: review
Abstract: Therapy-related myeloid neoplasms (t-MN) are a distinct subgroup of myeloid malignancies with a poor prognosis that include cases of therapy-related myelodysplastic syndrome (t-MDS), therapy-related myeloproliferative neoplasms (t-MPN) and therapy-related acute myeloid leukemia (t-AML). Here, we report a series of patients with clinical features consistent with juvenile myelomonocytic leukemia (JMML), an overlap syndrome of MDS and myeloproliferative neoplasms that developed after treatment for another malignancy.
DOI: 10.1002/pbc.29499
Authors: Astrid Wintering, Stephen Smith, Beng Fuh, Arun Rangaswami, Gary Dahl, May Chien, Tanja A. Gruber, Jinjun Dang, Loretta S. Li, Alicia Lenzen, Stephanie Savelli, Christopher C. Dvorak, Anurag K. Agrawal, Elliot Stieglitz
Institutions: University of California, San Francisco, UCSF Benioff Children's Hospital, East Carolina University, Stanford Medicine, Stanford University, Lurie Children's Hospital, Akron Children's Hospital, UCSF Helen Diller Family Comprehensive Cancer Center
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: green
OpenAlex ID: W4200118702
FWCI: 0.175
Cites: 33
Cited by: 6
Related to: 10