Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study
Year: 2021
Type: review
Study design: Observational Study
Source: Diabetologia
Authors: Carolina G. Downie, Sofia F. Dimos, Stephanie A. Bien, Yao Hu, Burcu F. Darst, Linda M. Polfus, Yujie Wang, Genevieve L. Wojcik, Ran Tao, Laura M. Raffield, Nicole D. Armstrong, Hannah G. Polikowsky, Jennifer E. Below, Adolfo Correa, Marguerite R. Irvin, Laura J. F. Rasmussen-Torvik, Christopher S. Carlson, Lawrence S. Phillips, Simin Liu, James S. Pankow, Stephen S. Rich, Jerome I. Rotter, Steven Buyske, Tara C. Matise, Kari E. North, Christy L. Avery, Christopher A. Haiman, Ruth J. F. Loos, Charles Kooperberg, Mariaelisa Graff, Heather M. Highland
Institutions: University of North Carolina at Chapel Hill, Fred Hutch Cancer Center, University of Southern California, Ambry Genetics (United States), Johns Hopkins University, Vanderbilt University Medical Center, University of Alabama at Birmingham, University of Mississippi Medical Center, Northwestern University, Emory University, Atlanta VA Medical Center, Brown University, University of Minnesota, University of Virginia, The Lundquist Institute, Harbor–UCLA Medical Center, Rutgers, The State University of New Jersey, Icahn School of Medicine at Mount Sinai
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
Funders: American Diabetes Association, U.S. Department of Veterans Affairs, National Institute for Nutrition and Health, National Institutes of Health, Gillings School of Public Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute on Drug Abuse, National Human Genome Research Institute, NIH Office of the Director, National Cancer Institute, National Institute of Allergy and Infectious Diseases, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Institute of Environmental Health Sciences, National Institute of Dental and Craniofacial Research, U.S. National Library of Medicine, National Center on Minority Health and Health Disparities, National Center for Research Resources, National Center for Advancing Translational Sciences, National Institute on Minority Health and Health Disparities, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1114307781, G1153393142, G1261314546, MESA, G1300756762, G1313217991, Epidemiology of putative genuine genetic variant: The Women's Health Intiative, G1409423729, VCID and Stroke in a Bi-racial National Cohort, Hispanic Community Health Study, G1459159051, Monitoring Social Change: Health and Human Capital from Childhood to Adulthood, G1515916771, G1539384734, Center for Clinical and Translational Sciences (CCTS), G1666450717, G1686417863, G177061346, G1803853571, G1888983140, G1900805147, G190379715, G196810821, Monitoring Social Change: Dynamics Of Aging And Cognitive Function, High-Performance Compute Cluster for Comprehensive Cancer and Infectious Diseases Research, G2127676537, G2128161193, G2223280742, G2262782284, G2286579242, G2316258288, G2331643373, Epidemiology of Putative Causal Variants in the Multiethnic Cohort, G2415573643, MESA, G243962516, Institute for Clinical and Translational Research (UL1), HISPANIC COMMUNITY HEALTH STUDY - FIELD CENTER, G2528054427, G2548880556, G2580996367, G2792355618, G2809357584, MESA, SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READING, G2970637568, G297113894, G3014393894, G3123615352, G3226771441, G3342643523, G3349065339, Hispanic Community Health Study, G3488149570, G3501153549, G350245564, G3527068412, G3570589137, Genetic Epidemiology of Causal Variants across the Life Course Phase II (CALiCo I, G3647016462, G3684451641, G3687594596, G370977179, Polygenic Risk Scores for Diverse Populations - Bridging Research and Clinical Care, GWA for Gene-Environment Interaction Effects Influencing CHD, MESA, G3863533586, G3892226038, G3896070745, G3901643820, G3964248905, G3973572274, G399481048, PAGE III: Population Architecture using Genomics and Epidemiology, G4143790175, G4156535370, TITLE: MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS (MESA), G4401737188, Hispanic Community Health Study, G4407350458, G4454205498, Emergence of Cardiometabolic Risk Across the Lifecycle in China, G4474940982, G4512137732, G4562300860, G4563812999, G4672149634, Inflammatory mediators of cardiometabolic risk in Latinos, G47192932, G4747441672, G4790942633, OPTION 3. 4/1/2014 - 3/31/2015. MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS (MESA) - READING CENTER, NHLBI, MESA, G506850682, G5088122703, GWAS of longitudinal blood pressure profiles from young adulthood to middle-age, G5108002584, G5130182543, G514410172, SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-ULTRASOUND, G5365244667, G537005415, G5372897717, G5380696608, HISPANIC COMMUNITY HEALTH STUDY - COORDINATING CENTER, Genome-Wide Association for Loci Influencing CHD and Other Heart, Lung and Blood, Center of Excellence for Diabetes in Americans of Mexican Descent, Epidemiology of Venous Thrombosis and Pulmonary Embolism, G5569049148, G571830633, G5770678025, G5787256936, G579045871, G580208524, A Genome-Wide Association Study of Ischemic Brain Vascular Injury, Continuation of the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study, CHARGE consortium: omics discovery for CVD and aging phenotypes, G5928944960, Study of coding variants in human obesity and their functional characterization using human iPSC-derived cellular models, G6075306088, G6095866717, G617038295, PAGE III: Population Architecture using Genomics and Epidemiology, G6173197892, G6178793362, G6182174406, G6238440229, G6238582308, G6347911464, G6359107525, Institute for Clinical and Translational Research, G6410032906, G642446049, MESA, Characterizing Genetic Susceptibility to Breast and Prostate Cancer; the BPC3, G6514094751, Transition to a Western diet and cardiometabolic risk: biomarkers derived from the microbiome, G6607318219, G6610578209, Nutrition-Related NCD Prevention Training in China, SNP HEALTH ASSOCIATION RESOURCE (SHARE), G6837735701, G6840217687, G6862617662, G6894818919, G693077865, G7032370290, G7091571603, G7132511053, G7155745631, MESA, G7435069916, G7481962703, G7535686976, G7660896353, G7667010295, G7697152668, G7821233859, Johns Hopkins Institute for Clinical and Translational Research, G786201135, Molecular Epidemiology of Nutrition and Cancer in the Multiethnic Cohort Study, G7990718016, G8005992114, G805888226, Clinical and Translational Science Award, G814392139, G836417160, Screening for IGT: Glucose Challenge vs Predictive Model, G855454396, G857355474, G8738262636, G8761005068, G8836210513, G8921806468, G89699440, Diabetes Research Center (DRC), Cardiovascular Epidemiology Training Grant, Cardiorenal Genomics for Risk Prediction in African Descent Populations, The Genetic Epidemiology of Heart, Lung, and Blood Traits Training Grant (GenHLB), NYR-Diabetes Research Center (NYR-DRC), Hispanic Latino Lipid Consortium, From GWAS loci to blood pressure genes, variants & mechanisms - Renewal, UCLA Clinical and Translational Science Institute, G929937216, G94668252
OpenAlex ID: W4200139297