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A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

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Year: 2021
Type: preprint
Source: Research Square
DOI: 10.21203/rs.3.rs-1034608/v1
Authors: Sundeep Khosla, Dominik Saul, Robyn Laura Kosinsky, Elizabeth Atkinson, Madison Doolittle, Xu Zhang, Nathan LeBrasseur, Robert Pignolo, Paul Robbins, Laura Niedernhofer, Yuji Ikeno, Diana Jurk, Joao Passos, LaTonya Hickson, Ailing Xue, David Monroe, Tamara Tchkonia, James Kirkland, Joshua Farr
Institutions: Mayo Clinic, University of Göttingen, University of Minnesota, The University of Texas at San Antonio Health Science Center, Mayo Clinic in Florida
Language: English

Topic: Telomeres, Telomerase, and Senescence
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Mayo Clinic, University of Minnesota, Noaber Foundation, Deutsche Forschungsgemeinschaft, Deutsche Krebshilfe, National Institutes of Health, National Institute on Aging
Awards: Zelldynamik in Pathogenese und Therapie, Targeting cellular senescence with senolytics to improve skeletal health in older humans, The role of sub-lethal mitochondrial apoptotic stress in cellular senescence, G9000046310, G9000069937, G9000153529, G9000209252, G9000236425, G9000295892, Effect of Aging on Preadipocyte Differentiation
OpenAlex ID: W4200207693
Cites: 106
Cited by: 6
Related to: 10
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