Work

Facile method to incorporate high-affinity ACAT/SOAT1 inhibitor F12511 into stealth liposome-based nanoparticle and demonstration of its efficacy in blocking cholesteryl ester biosynthesis without overt toxicity in neuronal cell culture

Year: 2021

Type: article

Source: Journal of Neuroscience Methods

DOI: 10.1016/j.jneumeth.2021.109437

Authors: Adrianna L. De La Torre, Caleb Smith, Joseph Granger, Faith L. Anderson, Taylor C. Harned, Matthew C. Havrda, Catherine C.Y. Chang, Ta-Yuan Chang

Institution: Dartmouth College

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke, National Institute of Environmental Health Sciences

Awards: Nanoparticles encapsulating a potent cholesterol storage inhibitor as a novel therapeutic to treat Alzheimer's disease, G1762870898, G3375594449, Mechanisms of chlorpyrifos-mediated programmed cell death in primary neurons, Alleviating lysosomal lipid defects in ADRD by blocking cholesterol storage, Mechanisms of pesticide-induced neuroinflammation and parkinsonism in aging mice, The Institute for Biomolecular Targeting

OpenAlex ID: W4200220809

FWCI: 0.653

Cites: 54

Cited by: 11

Related to: 10