Work

The detrimental effects of APOE4 on risk for Alzheimer's disease may result from altered dendritic spine density, synaptic proteins, and estrogen receptor alpha

Year: 2021

Type: article

Source: Neurobiology of Aging

DOI: 10.1016/j.neurobiolaging.2021.12.006

Authors: Lisa R. Taxier, Sarah M. Philippi, Jason M. York, Mary Jo LaDu, Karyn M. Frick

Institutions: University of Wisconsin–Milwaukee, University of Illinois Chicago

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Alzheimer's Association, National Institutes of Health, National Institute on Aging, National Institute of Mental Health, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke

Awards: The role of hippocampal astrocytes in memory and estrogenic regulation of memory, G2813544401, Development of ER-beta Agonists to Treat Post-Menopausal Memory Decline, G3284267011, G365222256, G4020510678, G5684452051, G6052127884, G629047069, Characterization of protective roles of ApoE2 against aging and Alzheimer's disease, Estrogen therapy and APOE4 risk in Alzheimer's tested in female EFAD mice, Estradiol-APOE interactions in a mouse model of AD, G9000043017, G9000193582

OpenAlex ID: W4200357017

FWCI: 1.431

Cites: 79

Cited by: 26

Related to: 10