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Proteomic profiling of key signatures from gastric lesions to early gastric cancer

Year: 2021
Type: article
Abstract: Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality. It is frequently diagnosed in advanced stages [1,2]. The development of GC is preceded by multi-stage precancerous process. However, molecular signatures underling the dynamic changes of gastric lesions and development of early GC are not well understood. Although recent genomic findings from genomic profiling will facilitate ‘next-generation’ clinical initiatives in GC precision oncology and prevention [3], the protein sequences/structures are further modulated by post-translational modifications.
Source: EBioMedicine
DOI: 10.1016/j.ebiom.2021.103744
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $3,500
Funders: U.S. Department of Defense, Welch Foundation, Gastric Cancer Foundation, National Institutes of Health, National Cancer Institute, DOD Peer Reviewed Cancer Research Program
Awards: G1220545696, Prediction of Pathologic Complete Response by Gene Expression Profiling in Esopha, G52711424, G5313717065, G7389384538, G7623734931, Inhibition of Hedgehog Signaling in Gli-1+Adeno CA of the Esoph or GE junction
OpenAlex ID: W4200361515
FWCI: 0.162
Cites: 10
Cited by: 2
Related to: 10