Reverted HIV-1 Mutants in CD4 + T-Cells Reveal Critical Residues in the Polar Region of Viral Envelope Glycoprotein
Year: 2021
Type: article
Abstract: Our previous mutagenesis study revealed that serine at position 534 of HIV-1 Env is critical for viral infectivity. We found that HIV-1 Env containing serine to proline mutation at position 534 (S534P) are incapable of supporting virus-cell and cell-cell fusion.
Source: Microbiology Spectrum
Authors: Wuxun Lu, Tai-Wei Li, Stacia Phillips, Li Wu
Institutions: The Ohio State University, University of Iowa
Language: English
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,500
OpenAlex ID: W4200370840