Work

More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer

Year: 2021

Type: article

Abstract: Microbes in the gut impact response, resistance, and toxicity to numerous cancer therapies, though mechanisms remain incompletely understood. Blake et al. provide further evidence that gut microbes promote toxicity to immune-agonistic antibodies, with opportunities to target these in cancer treatment. 1

Source: Cell Reports Medicine

DOI: 10.1016/j.xcrm.2021.100482

Authors: Manoj Chelvanambi, Jennifer A. Wargo

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,200