Work

Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells

Year: 2021

Type: review

Abstract: Follicle stimulating hormone (FSH) and its receptor (FSHR) have been reported to be responsible for several physiological functions and cancers. The responsiveness of stem cells and cancer stem cells towards the FSH-FSHR system make the function of FSH and its receptors more interesting in the context of cancer biology. This review is comprised of comprehensive information on FSH-FSHR signaling in normal physiology, gonadal stem cells, cancer cells, and potential options of utilizing FSH-FSHR system as an anti-cancer therapeutic target.

Source: International Journal of Biological Sciences

DOI: 10.7150/ijbs.63721

Authors: Swati Haldar, Himanshu Agrawal, Sarama Saha, Alex R. Straughn, Partha Roy, Sham S. Kakar

Institutions: Indian Institute of Technology Roorkee, All India Institute of Medical Sciences Rishikesh, University of Louisville

Language: English

Topic: Reproductive Biology and Fertility

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,337