Year: 2010
Type: article
Abstract: maneuvers, 20% were prone positioned, 5% had high-frequency oscillation ventilation, 32% received nitric oxide, and 22% received prostacyclin.The initial mode of ECMO was venovenous in 93% of the patients.The median duration of ECMO support was 10 days, and the median circuit blood flow at 24 h was 4.9 l/min.Hemorrhagic and infectious complications occurred in 54 and 62% of the patients, respectively, during ECMO therapy.Compared with patients who underwent conventional treatment, patients who received ECMO had a longer duration of mechanical ventilation (18 vs. 8 days, P ϭ 0.001), a longer ICU length of stay (22 vs. 12 days, P ϭ 0.001), and a higher mortality rate (23 vs. 9%, P ϭ 0.01).Hemorrhagic complications were associated with 74% of deaths in the ECMO group. InterpretationDespite the limitations of this study (e.g., randomization, ECMO use timing, and transfer organization), overall mortality was low in the conventional group and the ECMO group.It may be hypothesized that a fast use of ECMO in ARDS before the onset of other organ failures is associated with a better outcome.However, this remains to be validated.
Source: Anesthesiology
Authors: J. Lance Lichtor, Joseph F. Antognini
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4205605388