Work

Systematic Genetic Interaction Analysis Identifies a Transcription Factor Circuit Required for Oropharyngeal Candidiasis

Year: 2022

Type: article

Abstract: The pathology of oral candidiasis has features of biofilm formation, a well-studied process in vitro . Based on that analogy, we hypothesized that the network of transcription factors that regulates in vitro biofilm formation has similarities and differences during oral infection.

Source: mBio

DOI: 10.1128/mbio.03447-21

Authors: Norma V. Solis, Rohan S. Wakade, Virginia E. Glazier, Tomye L. Ollinger, Melanie Wellington, Aaron P. Mitchell, Scott G. Filler, Damian J. Krysan

Institutions: University of California, Los Angeles, The Lundquist Institute, Harbor–UCLA Medical Center, University of Iowa, Niagara University, University of Georgia

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: National Institute of Allergy and Infectious Diseases, National Institute of Dental and Craniofacial Research

Awards: G1954364484, Complex haploinsufficiency based genetic analysis of C. albicans pathogenesis, G6034577002

OpenAlex ID: W4205635481

FWCI: 1.923

Cites: 36

Cited by: 21

Related to: 10