Work

Biomimetic Scaffolds Modulate the Posttraumatic Inflammatory Response in Articular Cartilage Contributing to Enhanced Neoformation of Cartilaginous Tissue In Vivo (Adv. Healthcare Mater. 1/2022)

Year: 2022

Type: article

Abstract: Cartilage Repair In article number 2101127 by Lewis W. Francis, Francesca Taraballi, and co-workers, a biomimetic immune tuning scaffold is implanted in a full-thickness chondral defect in rabbits. The early inflammatory infiltrates changed in the treated animals resulting in a better cartilage homeostasis at longer timepoints. This work represents the first approach of tuning the inflammatory reaction with a bulk material to achieve a better regeneration in cartilage.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.202270002

Authors: Guillermo Bauza‐Mayol, Marcos Quintela, Ava Brozovich, Michael Hopson, Shazad Shaikh, Fernando Cabrera, Aaron Shi, Federica Banche Niclot, Francesca Paradiso, Emman Combellack, Tom Jovic, Paul Rees, Ennio Tasciotti, Lewis W. Francis, Patrick Mcculloch, Francesca Taraballi

Language: English

Topic: Osteoarthritis Treatment and Mechanisms

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4205770210

FWCI:

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