Work

Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site

Year: 2022

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2022.128571

Authors: Nicholas L. Yan, Reji Nair, Alan Chu, Ian A. Wilson, Kristen A. Johnson, Gareth J. Morgan, Jeffery W. Kelly

Institutions: Scripps Research Institute, California Institute for Biomedical Research, Boston University

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: U.S. Department of Energy, National Institutes of Health, Office of Science, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, Office of Research Infrastructure Programs, National Institutes of Health, Argonne National Laboratory

Awards: G107546177, G2027980179, High-Speed High-Sensitivity Detector for X-ray Micro-Crystallography at GM/CA@APS, G3913106684, G466926004, G6579817608, G8473838722, G8927075130, G9000172603, G9000327446, GM/CA@APS: A Macromolecular Crystallography Resource, Probing the Proteinopathy Component of Light Chain Amyloidosis Pharmacologically

OpenAlex ID: W4205812302

FWCI: 0.483

Cites: 35

Cited by: 8

Related to: 10