Year: 2022
Type: article
Abstract: ### What you need to know Extreme preterm birth, defined as birth before 28 weeks’ gestational age (box 1),1 affects about two to five in every 1000 pregnancies, and varies slightly by country and by definitions used. Severe maternal morbidity, including sepsis and peripartum haemorrhage, affects around a quarter of mothers delivering at these gestations.2 For the babies, survival and morbidity rates vary, particularly by gestational age at delivery but also according to other risk factors (birth weight and sex, for example) and by country.34 In this update, we focus on high income countries and provide a broad overview of extreme preterm birth epidemiology, recent changes, and best practices in obstetric and neonatal management, including new treatments such as antenatal magnesium sulphate or changes in delivery management such as delayed cord clamping and placental transfusion. We cover short and long term medical, psychological, and experiential consequences for individuals born extremely preterm, their mothers and families, as well as preventive measures that may reduce the incidence of extreme preterm birth. Box 1 ### Key definitions #### World Health Organization definitions relating to preterm birth #### Preterm #### Moderate to late pretermRETURN TO TEXT
Source: BMJ
Authors: Andrei S Morgan, Marina Mendonça, Nicole Thiele, Anna L David
Institutions: University of London, Inserm, Université Paris Cité, Assistance Publique – Hôpitaux de Paris, Maternité Port Royal, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche Épidémiologie et Statistique, University College London, University of Leicester, University of Warwick, National Institute for Health and Care Research, UCL Biomedical Research Centre
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funder: European Commission
OpenAlex ID: W4206682480