Work

In vivo contactless brain nanothermometry

Year: 2018

Type: article

Abstract: Despite attracting increased attention from clinicians, brain temperature distribution, fluctuations and changes in response to external stimuli are still largely unknown and refractory to conventional temperature-probing approaches. Fluorescence nanothermometry in the second near-infrared window (NIR-II window, 1,000-1,700 nm), as shown here, can provide contactless brain thermal sensing through the scalp and skull in real-time with a sub-degree resolution. As a proof of concept, Ag2S nanothermometers have been used to monitor brain thermoregulation in a cooling/heating process and temperature changes associated with a barbiturate coma.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.3549577

Authors: del Rosal, Blanca, Ruiz, Diego, Chaves-Coira, Irene, H. Juárez, Beatriz, Monge, Luis, Hong, Guosong, Fernández, Nuria, Jaque, Daniel

Institutions: Swinburne University of Technology, IMDEA Nanoscience, Universidad Autónoma de Madrid, Harvard University, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Universitario Ramón y Cajal

Language: English

Topic: Luminescence Properties of Advanced Materials

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: European Commission, Ministerio de Economía y Competitividad, Instituto de Salud Carlos III

Awards: G1075404386, Nanoparticles-based 2D thermal bioimaging technologies, G1659218285, G1936523210, G2708544407, G3403184308, G4042169593, G4435369794, Obtención de imagen diagnóstica molecular intracoronaria in vivo mediante el uso de Tomografía de Coherencia Óptica y nanopartículas funcionalizadas., G5285568709, G6969271195

OpenAlex ID: W6931176524

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