Whole-organ deceased donor tracheal allograft transplantation for the treatment of refractory tracheal stenosis: a case report
Year: 2022
Type: article
Study design: Case Report
Abstract: Tracheal stenosis involving >5 cm of trachea is debilitating for patients, impedes their quality of life and may even become life-threatening. Large, open defects often result in these patients because of multiple failed tracheal resections and endoscopic dilatations. Tracheal transplantation has been proposed as a curative solution, but revascularization of the trachea as an allograft has generally been considered prohibitively challenging due to a tenuous blood supply. We report a multidisciplinary effort resulting in the first vascularized, single-stage, deceased donor tracheal allograft transplantation in a woman with long-segment tracheal stenosis.
Authors: Shane C. Dickerson, Eric M. Genden, Caroline R. Gross, Sander S. Florman, Eric Franz, Daniel Chang, Samuel DeMaria
Institution: Icahn School of Medicine at Mount Sinai
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4206773042