Work

Adolescent Medicine Trials Network for HIV/AIDS Interventions Data Harmonization: Rationale and Development of Guidelines

Year: 2018

Type: article

Abstract: BACKGROUND: The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) research program aims to defeat the rising HIV epidemic among adolescents and young adults in the United States. OBJECTIVE: This study aims to optimize cross-study analyses and comparisons of standardized measures (variables) collected in the ATN. METHODS: Guidelines were developed for harmonizing measures to be collected across ATN studies. RESULTS: Eight domains were identified for harmonization-Demographics and Socioeconomic Characteristics, Sexual Behavior and Risk, Substance Use and Abuse, HIV-Positive Cascade, HIV-Negative Cascade, Mental Health, Social Support and Isolation, and Pre-exposure Prophylaxis Cascade. CONCLUSIONS: The collection of selected key measures in a uniform manner across studies facilitates the characterization of participant populations, comparisons between studies, and pooled analysis of data from multiple studies.

Source: JMIR Research Protocols

DOI: 10.2196/11207

Authors: Micah McCumber, Demetria Cain, Sara LeGrand, Kenneth H Mayer, Debra A Murphy, Matthew A Psioda, Arlene C Seña, Tyrel J Starks, Michael Hudgens

Institutions: University of North Carolina at Chapel Hill, Hunter College, Duke University, Fenway Health, University of California, Los Angeles

Language: English

Topic: HIV/AIDS Research and Interventions

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,900

Funders: National Institutes of Health, National Institute of Mental Health, National Institute on Drug Abuse, National Institute of Allergy and Infectious Diseases, National Institute of Child Health and Human Development, National Institute on Minority Health and Health Disparities, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1145090516, G1190616174, G1312281137, The UNC/Emory Center for Innovative Technology (iTech) across the prevention and care continuum, G2232103862, A Comprehensive Community-based Strategy to Optimize the HIV Prevention and Treatment Continuum for Youth At HIV Risk, Acutely Infected and with Established HIV Infection, G4597269444, G4749080892, G6787058494, G9000114984, G9000339749, The University of North Carolina Center for AIDS Research

OpenAlex ID: W2891779850

FWCI: 1.136

Cites: 34

Cited by: 18

Related to: 10