Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation
Work
Year: 2021
Type: article
Abstract: CDK4/6 inhibitors are approved to treat breast cancer and are in trials for other malignancies. We examined CDK4/6 inhibition in mouse and human CD8+ T cells during early stages of activation. Mice r... more
Source: Cancer Discovery
Institutions Dana-Farber Cancer Institute, Harvard University, Massachusetts General Hospital, Icahn School of Medicine at Mount Sinai, Peter MacCallum Cancer Centre +1 more
Cites: 55
Cited by: 62
Related to: 10
FWCI: 14.34
Citation percentile (by year/subfield): 100
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Sustainable Development Goal Good health and well-being
Open Access status: bronze
Funders Susan G. Komen, German-Israeli Foundation for Scientific Research and Development, National Institutes of Health, Ludwig Center at Harvard, National Health and Medical Research Council
Grant IDS CCR18547966, 398222819, T32CA207021, U01 CA224146-01, GNT 1177357