Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice
Work
Year: 2022
Type: article
Abstract: In Huntington's disease (HD), the uninterrupted CAG repeat length, but not the polyglutamine length, predicts disease onset. However, the underlying pathobiology remains unclear. Here, we developed ba... more
Source: Neuron
Institutions University of California, Los Angeles, University of Florida, University of Alabama at Birmingham, University College London
Cites: 99
Cited by: 50
Related to: 10
FWCI: 6.884
Citation percentile (by year/subfield): 99.98
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
APC paid (est): $9,080