Year: 2022
Type: review
Abstract: Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug therapy as well as lifestyle changes. There is now growing scientific evidence to support the effectiveness of the use of herbal supplements in the prevention and control of diabetes. Curcumin is one of the most studied bioactive components of traditional medicine, but its physicochemical characteristics are represented by low solubility, poor absorption, and low efficacy. Nanotechnology-based pharmaceutical formulations can help overcome the problems of reduced bioavailability of curcumin and increase its antidiabetic effects. The objectives of this review were to review the effects of nanocurcumin on DM and to search for databases such as PubMed/MEDLINE and ScienceDirect. The results showed that the antidiabetic activity of nanocurcumin is due to complex pharmacological mechanisms by reducing the characteristic hyperglycemia of DM. In light of these results, nanocurcumin may be considered as potential agent in the pharmacotherapeutic management of patients with diabetes.
Source: BioMed Research International
DOI: 10.1155/2022/1375892
Institutions: Arturo Prat University, Universidad de La Frontera, Universidad Santo Tomás, Lahore Garrison University, National University of Sciences and Technology, Istanbul Aydın University, Sivas Cumhuriyet Üniversitesi, Slovak University of Agriculture in Nitra, Taras Shevchenko National University of Kyiv, University of Concepción, Universidad del Azuay, University of Medicine and Pharmacy of Craiova
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $2,680
OpenAlex ID: W4210785929