Work

The Staphylococcus aureus CidA and LrgA Proteins Are Functional Holins Involved in the Transport of By-Products of Carbohydrate Metabolism

Year: 2022

Type: article

Abstract: genes encode proteins with bacteriophage holin-like functions, consistent with their roles in cell death. However, these studies also demonstrate that these operons are involved in the transport of small metabolic by-products of carbohydrate metabolism, suggesting an intriguing link between these two seemingly disparate processes.

Source: mBio

DOI: 10.1128/mbio.02827-21

Authors: Jennifer L. Endres, Sujata S. Chaudhari, Xinyan Zhang, Janani Prahlad, Shu-Qi Wang, Lily A. Foley, Sorin Luca, Jeffrey L. Bose, Vinai C. Thomas, Kenneth W. Bayles

Institutions: University of Nebraska Medical Center, University of Kansas Medical Center

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,900

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: Staphylococcal Biofilm and Disease, G3824564667, The role of arginine catabolic pathways in modulating staphylococcal fitness, G9000008107

OpenAlex ID: W4210789274

FWCI: 4.302

Cites: 51

Cited by: 38

Related to: 10