Year: 2019
Type: article
Abstract: People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between sequence features and other molecular species . Some typical practices and conventions have begun to emerge for such diagrams. The Synthetic Biology Open Language Visual (SBOL Visual) has been developed as a standard for organizing and systematizing such conventions in order to produce a coherent language for expressing the structure and function of genetic designs. This document details version 2.1 of SBOL Visual, which builds on the prior SBOL Visual 2.0 standard by expanding diagram syntax to include methods for showing modular structure and mappings between elements of a system, interactions arrows that can split or join (with the glyph at the split or join indicating either superposition or a chemical process), and adding new glyphs for indicating genomic context (e.g., integration into a plasmid or genome) and for stop codons.
Authors: Curtis Madsen, Angel Goni Moreno, Zachary Palchick, Umesh P, Nicholas Roehner, Bryan Bartley, Swapnil Bhatia, Shyam Bhakta, Mike Bissell, Kevin Clancy, Robert Sidney Cox, Thomas Gorochowski, Raik Grunberg, Augustin Luna, James McLaughlin, Tramy Nguyen, Nicolas Le Novere, Matthew Pocock, Herbert Sauro, James Scott-Brown, John T. Sexton, Guy-Bart Stan, Jeffrey J. Tabor, Christopher A. Voigt, Zach Zundel, Chris Myers, Jacob Beal, Anil Wipat
Institutions: Boston University, Newcastle University, Zymergen (United States), APJ Abdul Kalam Technological University, Rice University, Amyris (United States), Thermo Fisher Scientific (United States), Kobe University, University of Bristol, King Abdullah University of Science and Technology, Harvard University, University of Utah, Babraham Institute, Newcastle Australia Institute of Higher Education, University of Washington, Imperial College London, Massachusetts Institute of Technology
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,187
Awards: G1015763213, G1511075568, How changes in nutrient availability are sensed and shape metabolism and growth, Engineering Fellowships for Growth: Systems and control engineering framework for robust and efficient synthetic biology, BrisSynBio: Bristol Centre for Synthetic Biology, Signalling mechanisms that determine the rate of ageing, How neutrophils detect and resolve infection and how this deteriorates with age, How autophagy and related processes are coordinated and important in adaption to changed nutrient availability and cell damage, G6371588837, G6580186668, G7255661211, G8194766601
OpenAlex ID: W4211002602