Year: 2016
Type: review
Abstract: Tau is a microtubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until its conformation in dimers, oligomers, and larger polymers in physiological and pathological situations.
Source: Frontiers in Aging Neuroscience
Institutions: Consejo Superior de Investigaciones Científicas, Biomedical Research Networking Center on Neurodegenerative Diseases, Centro de Investigación Biomédica en Red, Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid, Universidad de La Laguna, Universidad de Cantabria, Instituto de Investigación Marqués de Valdecilla, Centro de Investigaciones Biológicas Margarita Salas
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4211132017