Work

The use of new CRISPR tools in cardiovascular research and medicine

Year: 2022

Type: review

Source: Nature Reviews Cardiology

DOI: 10.1038/s41569-021-00669-3

Authors: Masataka Nishiga, Chun Liu, Lei S. Qi, Joseph C. Wu

Institutions: Stanford Medicine, Stanford Cardiovascular Institute, Stanford University

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Science Foundation, American Heart Association, Tobacco-Related Disease Research Program, Fondation Leducq, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G1025848449, Modeling Susceptibility to Chemotherapy-Induced Cardiotoxicity Using Human iPSCs, G3331948458, CAREER: Investigating Chromatin Dynamics Underlying Activity-Induced Neuronal Transcription Using CRISPR Technologies, Towards Precision Medicine with Human iPSCs for Cardiac Channelopathies, G3831649810, G4097614321, Engineering and Imaging 3D genome structure-function dynamics across time scales, Targeting Endothelial Cells Modulation for Cardiolaminopathy Treatment, G5058312027, G5171724592, G5316616671, Genome Editing of Human iPSCs to Study Inherited Hypertrophic Cardiomyopathy, G6671297155, G6955760727, Precision Medicine and Clinical Trial in a Dish for Cardiovascular Diseases, G795658879, G822580573, Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated Cardiomyopathy, Single-cell Multi-omic Profiling of Drug Responses Using Pooled iPSC-CM Differentiation, Modeling Tyrosine Kinase Inhibitor-Induced Vascular Dysfunction Using Human iPSCs, Elucidating Anthracycline-Induced Cell Type-Specific Cardiovascular Toxicity with CRISPRi/a Screens

OpenAlex ID: W4211161436

FWCI: 1.373

Cites: 158

Cited by: 67

Related to: 10