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Crystal and cryo-EM structures provide insight into how pro-neurodegenerative SARM1 is activated and cleaves NAD+

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Year: 2021
Type: article
Source: Acta Crystallographica Section A Foundations and Advances
DOI: 10.1107/s0108767321092552
Authors: Thomas Ve, Weixi Gu, Jeffrey D. Nanson, Yun Shi, Katie Cunnea, Philip S. Kerry, Todd Bosanac, Robert O. Hughes, Bostjan Kobe
Institutions: Griffith University, The University of Queensland, Evotec (United Kingdom), Disarm Therapeutics (United States)
Language: English

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: bronze
OpenAlex ID: W4211258502
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Related to: 10
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