Work

Peptide probes for proteases – innovations and applications for monitoring proteolytic activity

Year: 2022

Type: review

Abstract: From a chemistry-based perspective, this review discusses the most recent advances in the field of substrate-based probes for the detection and analysis of proteolytic activity both in vitro and in vivo .

Source: Chemical Society Reviews

DOI: 10.1039/d1cs00798j

Authors: Maria Rodriguez-Rios, Alicia Megia-Fernandez, Daniel J. Norman, Mark Bradley

Institutions: University of Edinburgh, Technical University of Munich

Language: English

Topic: Protease and Inhibitor Mechanisms

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funders: University of Edinburgh, Engineering and Physical Sciences Research Council

Awards: EPSRC IRC Proteus - Multiplexed 'Touch and Tell' Optical Molecular Sensing and Imaging - Lifetime and Beyond, G789800706

OpenAlex ID: W4213044540

FWCI: 2.031

Cites: 265

Cited by: 94

Related to: 10