Work

Author response: SWI/SNF senses carbon starvation with a pH-sensitive low-complexity sequence

Year: 2022

Type: peer-review

Abstract: A combination of single-cell analysis, genomics, and simulations shows that a glutamine-rich low-complexity sequence in the SWI/SNF chromatin remodeling complex senses transient intracellular acidification as a signal for cells to switch their global transcriptional program.

DOI: 10.7554/elife.70344.sa2

Authors: J Ignacio Gutierrez, Gregory P Brittingham, Yonca Karadeniz, Kathleen D Tran, Arnob Dutta, Alex S Holehouse, Craig L Peterson, Liam J Holt

Institutions: University of California, Berkeley, New York University, University of Massachusetts Chan Medical School, University of Rhode Island, Washington University in St. Louis

Language: English

Topic: Chromatin Remodeling and Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W4214817666

Cites:

Cited by:

Related to: 10