Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration
Work
Year: 2022
Type: article
Abstract: SignificanceNeurodegenerative diseases are poorly understood and difficult to treat. One common hallmark is lysosomal dysfunction leading to the accumulation of aggregates and other undegradable mater... more
Institutions Stanford University, Neurosciences Institute, Palo Alto Veterans Institute for Research, SRI International, Menlo School
Cites: 80
Cited by: 37
Related to: 10
FWCI: 7.756
Citation percentile (by year/subfield): 100
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Sustainable Development Goal Good health and well-being
Open Access status: hybrid
Funders Michael J. Fox Foundation for Parkinson's Research, Glenn Foundation for Medical Research, Life Sciences Research Foundation, National Institute on Aging, National Institute of Neurological Disorders and Stroke
Grant IDS ASAP, fellowship, fellowship, AG054407, NS057496