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Phase II study of dichloroacetate, an inhibitor of pyruvate dehydrogenase, in combination with chemoradiotherapy for unresected, locally advanced head and neck squamous cell carcinoma

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Year: 2022
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Source: Investigational New Drugs
DOI: 10.1007/s10637-022-01235-5
Authors: Steven F. Powell, Miroslaw Mazurczak, Elie G. Dib, Jonathon S. Bleeker, Louis H. Geeraerts, Matthew Tinguely, Michele M. Lohr, Steven C. McGraw, Ashley W. Jensen, Christie A. Ellison, Lora J. Black, Susan E. Puumala, Valerie J. Reed, W. Keith Miskimins, John H. Lee, William C. Spanos
Institutions: Sanford Health, University of South Dakota, Sanford Research, Avera Health
Language: English

Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Dental and Craniofacial Research
Awards: Immune Dysregulation by Human Papillomavirus during Head and Neck Cancer Progression, Chemokine-mediated antigen-specific T cell responses and immunotherapies to treat head and neck cancer, G8314218910, Center for Cancer Biology
OpenAlex ID: W4220811415
FWCI: 10.36
Cites: 37
Cited by: 63
Related to: 10
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