Work

Author response: CaV2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury

Year: 2022

Type: peer-review

Abstract: High mortality following traumatic brain injury in mice carrying a human mutation for familial hemiplegic migraine type 1 (FHM1) is caused by a decreased threshold for cortical spreading depolarizations (CSDs) and subsequent brain edema formation.

Source: eLife

DOI: 10.7554/elife.74923.sa2

Authors: Nicole A Terpolilli, Reinhard Dolp, Kai Waehner, Susanne M Schwarzmaier, Elisabeth Rumbler, Boyan Todorov, Michel D Ferrari, Arn MJM van den Maagdenberg, Nikolaus Plesnila

Institutions: Munich Cluster for Systems Neurology, München Klinik, Institut für Schlaganfall- und Demenzforschung, University of Mannheim, Leiden University Medical Center

Language: English

Topic: Migraine and Headache Studies

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W4221004102

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